Acute Inflammation

From now on I intend to only include the introduction of learning articles, that way you dont have to scroll for ages to get the information you need. To view and download this 9 page article on acute inflammation, visit


Acute inflammation is the immediate response to an inflammatory agent (such as a pathogen or foreign material) or necrotic cells/tissue caused by cell injury and death. It undergoes many vascular changes in order to increase the amount of antibodies and leukocytes at the site of inflammation. The major contributing factors are:

  1. Alterations in the vascular flow and calibre – increasing blood flow
  2. Structural changes of the microvasculature (capillaries, arterioles and venules) – Resulting in the leakage of plasma proteins (e.g. fibrin) and the evasion of leukocytes
  3. Emigration of leukocytes from the microcirculation – Resulting in the accumulation of leukocytes in the area of injury
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